This article examines the rare phenomenon of mainstream Euroscepticism that has characterised the British Conservative Party and asks whether a similar pattern has appeared elsewhere in the EU. The study traces the long-term evolution of salience and positions on the EU issue in the manifestos of a heterogenous set of centre-right parties, paying particular attention to whether Brexit or successive EU crises have had some noticeable effect. The thesis of Tory exceptionalism is largely supported by the findings – no other mainstream conservative party in the EU has talked more, and more negatively, about the EU over a long time period. Most other centre-right parties were part of the permissive consensus on the EU and have supported, more or less openly, the integration project throughout the past 30 years. However, some parties of mainstream conservatism have shown a similar negative shift as British Conservatives did in the 2000s, such as the Austrian ÖVP, the Hungarian Fidesz, the Polish PiS and (marginally) the Dutch VVD. Being in opposition or pressured by radical right challengers does not necessarily make the mainstream right more critical of the EU. Internal organisational developments (i.e. the ascent of more Eurosceptic influences within the party) constitute the most convincing proximate explanation for mainstream Euroscepticism on the right.